Cezary Dziekoński, Eng


Recent publications
1.Fura Ł., Dera W., Dziekoński C., Świątkiewicz M., Kujawska T., Experimental evaluation of targeting accuracy of ultrasound imaging-guided robotic HIFU ablative system for the treatment of solid tumors in pre-clinical studies, APPLIED ACOUSTICS, ISSN: 0003-682X, DOI: 10.1016/j.apacoust.2021.108367, Vol.184, pp.108367-1-9, 2021
Abstract:

We have designed and built low-cost compact ultrasound imaging-guided robotic HIFU (High-Intensity Focused Ultrasound) ablation device for thermal damage of solid tumors in small animals. Before this device is used to treat animals, experimental studies on ex vivo tissues were necessary to assess the accuracy of its targeting, ensuring the safety of therapy. The objective of this study was to assess the targeting accuracy of our device in the focal and axial plane of the HIFU beam using ex vivo tissue embedded in a reference cylindrical chamber inside which a coaxial cylindrical volume with a smaller diameter was ablated. HIFU beams with selected acoustic parameters, generated by a singe-element bowl-shaped 64-mm HIFU transducer operating at 1.08 MHz or 3.21 MHz frequency, were propagated in two-layer media: water-tissue (50 mm-40 mm) and focused at 12.6-mm depth below the tissue surface. Cylindrical necrotic lesions of various size were created by moving the chamber using a computercontrolled precise positioning unit. Lesions formed were compared with those intended for treatment using various visualization methods and displacement between their centers were determined. The targeting accuracy in the focal and axial planes was found to be respectively about 98% and 86% when determined from photos and about 88% and 76% when determined from MR images. The displacement between the centers of the necrotic lesion formed and planned for treatment was about 1 mm in the focal plane and about 2 mm in the axial plane. Our ablation device can be used as an effective and safe tool to plan, monitor and treat solid tumors in small animals and to test new anti-cancer drugs in preclinical studies.

Affiliations:
Fura Ł.-IPPT PAN
Dera W.-IPPT PAN
Dziekoński C.-IPPT PAN
Świątkiewicz M.-Mossakowski Medical Research Centre, Polish Academy of Sciences (PL)
Kujawska T.-IPPT PAN
2.Fura Ł., Dera W., Dziekoński C., Świątkiewicz M., Kujawska T., Experimental assessment of the impact of sonication parameters on necrotic lesions induced in tissues by HIFU ablative device for preclinical studies, ARCHIVES OF ACOUSTICS, ISSN: 0137-5075, DOI: 10.24425/aoa.2021.136573, Vol.46, No.2, pp.341-352, 2021
Abstract:

We have designed and built ultrasound imaging-guided HIFU ablative device for preclinical studies on small animals. Before this device is used to treat animals, ex vivo tissue studies were necessary to determine the location and extent of necrotic lesions created inside tissue samples by HIFU beams depending on their acoustic properties. This will allow to plan the beam movement trajectory and the distance and time intervals between exposures leading to necrosis covering the entire treated volume without damaging the surrounding tissues. This is crucial for therapy safety. The objective of this study was to assess the impact of sonication parameters on the size of necrotic lesions formed by HIFU beams generated by 64-mm bowl-shaped transducer used, operating at 1.08 MHz or 3.21 MHz. Multiple necrotic lesions were created in pork loin samples at 12.6-mm depth below tissue surface during 3-s exposure to HIFU beams with fixed duty-cycle and varied pulse-duration or fixed pulse-duration and varied duty-cycle, propagated in two-layer media: water-tissue. After exposures, the necrotic lesions were visualized using magnetic resonance imaging and optical imaging (photos) after sectioning the samples. Quantitative analysis of the obtained results allowed to select the optimal sonication and beam movement parameters to suport planning of effective therapy.

Keywords:

automated ultrasound imaging-guided HIFU ablation system, ex vivo tissue, ultrasonic exposure parameters, extent of necrotic lesions

Affiliations:
Fura Ł.-IPPT PAN
Dera W.-IPPT PAN
Dziekoński C.-IPPT PAN
Świątkiewicz M.-Mossakowski Medical Research Centre, Polish Academy of Sciences (PL)
Kujawska T.-IPPT PAN
3.Jarząbek D.M., Dziekoński C., Dera W., Chrzanowska J., Wojciechowski T., Influence of Cu coating of SiC particles on mechanical properties of Ni/SiC co-electrodeposited composites, CERAMICS INTERNATIONAL, ISSN: 0272-8842, DOI: 10.1016/j.ceramint.2018.08.271, Vol.44, pp.21750-21758, 2018
Abstract:

In this paper, the study of the mechanical properties of composites consisting of electrodeposited Ni and co-electrodeposited SiC particles coated with a thin Cu layer was presented. It was demonstrated that the coating allowed to increase the concentration of ceramic particles in the composite. Although the plating parameters were the same for both types of composites, the concentration of SiC was 15% for the composite containing coated particles (Ni/SiC-Cu) and 10% for the composite containing uncoated particles (Ni/SiC). Furthermore, tensile tests showed that the Ni/SiC-Cu samples exhibited higher Young's modulus than the pure electrodeposited Ni samples or Ni/SiC samples. The measured Young's modulus of the Ni/SiC-Cu composite was 250 ± 10 GPa. However, the ultimate tensile strength of the Ni/SiC-Cu composite was lower than that of pure Ni. To explain the mechanical behaviour of the Ni/SiC-Cu composite, the microstructure of the interface of this composite and its bonding strength were studied. Microstructure studies conducted using a scanning electron microscope (SEM) revealed that the SiC/Cu interface was smooth and of good quality whereas the Cu/Ni interface was rough but also of good quality. The measured bonding, normal, and shear strength values demonstrated that the SiC/Cu interface was weak, and that was the main reason for the low ultimate tensile strength of the composite. The shear strength of the SiC/Cu interface was measured using a novel method: micropillars shearing including atomic force microscopy (AFM). Finally, a simple finite element model of the Ni/SiC-Cu composite, based on cohesive elements, was developed.

Keywords:

Interfacial bonding strength, Metal matrix composites, Tensile strength, Silicon carbide, Electrodeposited nickel

Affiliations:
Jarząbek D.M.-IPPT PAN
Dziekoński C.-IPPT PAN
Dera W.-IPPT PAN
Chrzanowska J.-IPPT PAN
Wojciechowski T.-Institute of Physics, Polish Academy of Sciences (PL)
4.Frąś L.J., Dziekoński C., Dera W., Jarząbek D.M., Piezoelectric bimorph as a high-sensitivity viscosity resonant sensor to test the anisotropy of magnetorheological fluid, REVIEW OF SCIENTIFIC INSTRUMENTS, ISSN: 0034-6748, DOI: 10.1063/1.5025123, Vol.89, No.10, pp.105111-1-7, 2018
Abstract:

In this paper, we present a device which is very sensitive for small changes in the viscosity of the investigated fluid. The main part of the device is a piezo-electric bimorph which consists of the brass shim with two piezo-ceramic layers on the opposite sides. One of them is responsible for generating vibrations, whereas the second one is meant to measure system response which is produced by the damping properties of the surrounding fluid. During the experiment, the cylindrical bar is forced to move by the series of sinusoidal waves with different frequencies and at constant amplitudes. The probe is immersed in the fluid and then the amplitude vs frequency and phase vs frequency curves are obtained. Next, one can determine the viscosity according to a proper mathematical model. The resonant frequency is related to the damping coefficient which depends on the viscosity of the surrender fluid and immersion depth of the probe. The coefficients necessary for calculating viscosity are obtained by fitting the resonance curve to the amplitude vs frequency data obtained from the experiment. The device has been applied to study the anisotropy of magnetorheological fluids. The weak anisotropy of viscosity has been observed. The highest value of viscosity was observed in the case of viscosity measurement in the direction orthogonal to the magnetic field and the lowest in the direction parallel to the magnetic field.

Affiliations:
Frąś L.J.-IPPT PAN
Dziekoński C.-IPPT PAN
Dera W.-IPPT PAN
Jarząbek D.M.-IPPT PAN
5.Dziekoński C., Dera W., Jarząbek D.M., Method for lateral force calibration in atomic force microscope using MEMS microforce sensor, ULTRAMICROSCOPY, ISSN: 0304-3991, DOI: 10.1016/j.ultramic.2017.06.012, Vol.182, pp.1-9, 2017
Abstract:

In this paper we present a simple and direct method for the lateral force calibration constant determination. Our procedure does not require any knowledge about material or geometrical parameters of an investigated cantilever. We apply a commercially available microforce sensor with advanced electronics for direct measurement of the friction force applied by the cantilever's tip to a flat surface of the microforce sensor measuring beam. Due to the third law of dynamics, the friction force of the equal value tilts the AFM cantilever. Therefore, torsional (lateral force) signal is compared with the signal from the microforce sensor and the lateral force calibration constant is determined. The method is easy to perform and could be widely used for the lateral force calibration constant determination in many types of atomic force microscopes.

Keywords:

A precise and direct method for lateral force calibration, Inaccuracy equal to approximately 2%, Wedge method is proven to give inaccurate results

Affiliations:
Dziekoński C.-other affiliation
Dera W.-IPPT PAN
Jarząbek D.M.-IPPT PAN
6.Jarząbek D.M., Milczarek M., Wojciechowski T., Dziekoński C., Chmielewski M., The effect of metal coatings on the interfacial bonding strength of ceramics to copper in sintered Cu-SiC composites, CERAMICS INTERNATIONAL, ISSN: 0272-8842, DOI: 10.1016/j.ceramint.2017.01.056, Vol.43, No.6, pp.5283-5291, 2017
Abstract:

Cu-SiC composites are very promising materials which have high thermal and electrical conductivity and may find many applications. Unfortunately, the main disadvantage of these materials is the dissolution of silicon in copper at elevated temperature, which significantly reduces their properties. In order to overcome this problem particles can be coated with a protective material before sintering. In this paper– the influence of three different metallic coatings on bonding strength were investigated. SiC particles were coated with tungsten, chromium or titanium. As reference a material with uncoated particles was prepared. The experiments were carried out with the use of microtensile tester. The highest increase in strength was observed in the case of chromium coating. On the other hand, the titanium coating, which was of very poor quality, decrease the bonding strength in comparison with uncoated particles. Furthermore, scanning electron and optical microscopes were used to determine the mechanism of debonding.

Keywords:

interfacial bonding strength, metal matrix composites, tensile strength, silicon carbide particles

Affiliations:
Jarząbek D.M.-IPPT PAN
Milczarek M.-other affiliation
Wojciechowski T.-Institute of Physics, Polish Academy of Sciences (PL)
Dziekoński C.-IPPT PAN
Chmielewski M.-Institute of Electronic Materials Technology (PL)
7.Kujawska T., Dera W., Dziekoński C., Automated bimodal ultrasound device for preclinical testing of HIFU technique in treatment of solid tumors implanted into small animals, HYDROACOUSTICS, ISSN: 1642-1817, Vol.20, pp.93-98, 2017
Abstract:

In Poland cancer is the second cause of death overall, and the first before 65. Demand for new anticancer therapies is increasing every year. The main objective of studies on medical and technical aspects of new anticancer methods is to reduce unwanted side effects and costs associated with conventional methods of treatment. Percutaneous (noninvasive) HIFU (High Intensity Focused Ultrasound) technique gives the chance to radically reduce both of these factors. The main goal of this work is automation of HIFU technology for producing thermal damage to the entire volume of a solid breast tumor implanted into a rat mammary gland using the proposed bi-modal ultrasound equipment, enabling the ultrasonic heating of a small volume within the tumor under the ultrasonic imaging control, as well as 3D scanning of the heating beam focus throughout the entire tumor volume. Design of the proposed equipment includes the heating probe of low frequency (about 1MHz), allowing penetration of pulsed focused waves into tissues, and the linear phased array probe of high frequency (from 4 MHz to 10 MHz), allowing visualization of the locally heated area inside the tumor in real time. Automatic 3D scanning of the heating beam focus provides the thermal damage to its entire volume.

Keywords:

High Intensity Focused Ultrasound beam, focal volume, tissue damage

Affiliations:
Kujawska T.-IPPT PAN
Dera W.-IPPT PAN
Dziekoński C.-other affiliation

Conference abstracts
1.Fura Ł., Dera W., Dziekoński C., Kujawska T., Evaluation of targeting accuracy of a robotic ultrasound imaging-guided HIFU ablation device for treating solid tumors in small animals, 2019 ICU Bruges, 2019 International Congress on Ultrasonics, 2019-09-03/09-06, Bruges (BE), pp.1, 2019
2.Fura Ł., Dera W., Dziekoński C., Kujawska T., Evaluation of influence of ultrasound exposure parameters on necrotic lesions induced in tissues by robotic ultrasound-guided HIFU ablation device, 2019 ICU Bruges, 2019 International Congress on Ultrasonics, 2019-09-03/09-06, Bruges (BE), pp.1, 2019
3.Jarząbek D.M., Harvey C., Levintant-Zayonts N., Daraio C., Dziekoński C., Wojciechowski T., Gniadek M., Pathak S., Mechanical properties of N+ion irradiated vertically aligned carbon nanotube arrays studied by nanoindentation, EUROMAT 2019, European Congress and Exhibition on Advanced Materials and Processes 2019, 2019-09-01/09-05, Stockholm (SE), No.PM6-5, pp.464, 2019
4.Fura Ł., Dera W., Dziekoński C., Kujawska T., Experimental evaluation of the impact of ultrasound exposure parameters on necrotic lesions induced in tissue by a robotic ultrasound-guided hifu ablation device for treating solid tumors in small animals, ISTU 2019, The 19th International Symposium for Therapeutic Ultrasound, 2019-06-13/06-15, Barcelona (ES), pp.1, 2019
5.Fura Ł., Dera W., Dziekoński C., Kujawska T., Experimental evaluation of the accuracy of targeting of a robotic ultrasound imaging-guided hifu ablation device for treating solid tumors in small animals, ISTU 2019, The 19th International Symposium for Therapeutic Ultrasound, 2019-06-13/06-15, Barcelona (ES), pp.1, 2019
6.Dziekoński C., Jarząbek D.M., Dera W., The investigation of fracture of Silicon nanopillars: study of intrinsic and external size effect., FFW, 7th International Conference on Fracture Fatigue and Wear, 2018-07-09/07-10, Ghent (BE), pp.1, 2018
Abstract:

A material strength depends on its microstructure, which in turn, is controlled by an engineering process. Quantification strongly depends on the characteristic length scale of a particular
microstructure. This microstructural, or intrinsic, size governs the mechanical properties and post-elastic material deformation at all sample dimensions, as the classical definition of ultimate tensile strength deems it to be an intensive property, therefore its value does not depend on the size of the test specimen. However, in the last years, the vast majority of uniaxial deformation experiments and computations on small-scale structures unambiguously demonstrated that at the micron and sub-micron scales, this definition no longer holds true. Study focuses on the both the intrinsic (i.e. microstructural, internal size effect) and extrinsic (i.e. sample size, external size effect) dimensions which play a non-trivial role in the mechanical properties and material deformation mechanisms, it is critical to develop an understanding of their interplay and mutual effects on the mechanical properties and material deformation, especially in small-scale structures. To obtain its properties and the influence of scale in this study, nanopillars made from silicon was made and then tested under atomic force microscope in lateral force microscopy (LMF) mode. The nanopillars were sheared using AFM probes and then with knowledge of shear force the mechanical properties were obtained. Nanopillars varied in pillar diameter and grain size. The study is focused on the investigation of mutual dependence fracture strength due to grain size and pillar diameter.

Affiliations:
Dziekoński C.-IPPT PAN
Jarząbek D.M.-IPPT PAN
Dera W.-IPPT PAN
7.Dera W., Dziekoński C., Jarząbek D.M., Manufacturing Method and Characterization of mechanical properties of laminated metal nanocomposites with graded layer thickness, TMS 2018, 147th Annual Meeting and Exhibition, 2018-03-11/03-15, Phoenix (US), pp.1, 2018
8.Dziekoński C., Manufacturing Method and Material Characterization of Nanocrystalline Nickel Coatings with Gradient Grain Size., TMS 2018, 147th Annual Meeting and Exhibition, 2018-03-11/03-15, Phoenix (US), pp.1, 2018
Abstract:

Nanocrystalline materials exhibit attractive mechanical properties compared to their coarse-grained counterparts. The values of these properties are mainly affected by the size of grains, so it is possible to control the properties of the material by controlling the grain size in the coating. Moreover, due to the fact that nanocrystalline coatings are often deposited on the coarse grained substrate there is sufficient influence of the grain size in the area close to the interface. Thus, a coating that would have a variable microstructure should have better mechanical properties. Hence, the aim of the presentation is to show the results of the investigation of gradient grain sized coatings of nanocrystalline Nickel fabricated using Pulsed Reversed Current electrodeposition. Gradient coatings have continuous change of grain size in the direction of deposition. The presentation focuses on the influence of the microstructure of the material on the strength and wear resistance.

Affiliations:
Dziekoński C.-IPPT PAN
9.Dera W., Dziekoński C., Jarząbek D.M., Method for lateral force calibration in atomic force microscope using MEMS microforce sensor, 8TH International Colloquium Micro-Tribology, 2017-09-11/09-13, Warszawa (PL), pp.1-1, 2017
10.Frąś L.J., Dziekoński C., Dera W., Jarząbek D.M., The anisotrophy of viscosity of magnetorheological fluid., 8TH International Colloquium Micro-Tribology, 2017-09-11/09-13, Warszawa (PL), pp.1-2, 2017
11.Jarząbek D.M., Dziekoński C., Chmielewski M., Measurement of adhesion between ceramics and copper in sintered Cu-SiC composites., 8TH International Colloquium Micro-Tribology, 2017-09-11/09-13, Warszawa (PL), pp.1-1, 2017
12.Dera W., Dziekoński C., Jarząbek D.M., Lateral force calibration in atomic force microscope using MEMS microforce sensor, EUROMAT 2017, European Congress and Exhibition on Advanced Materials and Processes, 2017-09-17/09-22, Thessaloniki (GR), pp.D2-P-TUE-P1-23-27-27, 2017
13.Dziekoński C., Jarząbek D.M., Dera W., Influence of mode of electrodeposition, grain size on mechanical propertice of electrodeposited nanocrystaline nickel coatings., EUROMAT 2017, European Congress and Exhibition on Advanced Materials and Processes, 2017-09-17/09-22, Thessaloniki (GR), pp.C1-II-P-THU-P2-9-38-38, 2017
14.Jarząbek D.M., Dziekoński C., Chmielewski M., Effect of metal coatings on the interfacial bonding strength of ceramics to copper in sintered Cu-SiC composites., EUROMAT 2017, European Congress and Exhibition on Advanced Materials and Processes, 2017-09-17/09-22, Thessaloniki (GR), pp.C5-O-FRI-PM1-17-18, 2017
15.Frąś L.J., Jarząbek D.M., Dziekoński C., Pęcherski R.B., Viscoplastic deformation of magnethoreological solids, SolMech 2016, 40th Solid Mechanics Conference, 2016-08-29/09-02, Warszawa (PL), No.P244, pp.1-2, 2016
Abstract:

The microsized (~10µm) ferroelements build the structure of magenthoreological (MR) fluid. This two phase material in neutral state behaves as a fluid but in magnetic field becomes a solid and has properties of elasto-viscoplastic material. This is due to the skeleton made by ferrolements connected into braids. The aim of the paper is to identify the physical mechanisms of deformation of such a structure with use of own set up for in situ microscopic observations.

Keywords:

magnethoreological solids, viscoplasticity, ferroelements, compression test, shear banding

Affiliations:
Frąś L.J.-IPPT PAN
Jarząbek D.M.-IPPT PAN
Dziekoński C.-IPPT PAN
Pęcherski R.B.-IPPT PAN
16.Dziekoński C., Dera W., Frąś L.J., Jarząbek D.M., Precise force sensors for micro and nanotensile tests., SolMech 2016, 40th Solid Mechanics Conference, 2016-08-29/09-02, Warszawa (PL), pp.1, 2016
17.Dera W., Dziekoński C., Jarząbek D.M., The measurement of viscosity of thin polymer films, SolMech 2016, 40th Solid Mechanics Conference, 2016-08-29/09-02, Warszawa (PL), pp.1, 2016

Patents
Filing No./Date
Filing Publication
Autor(s)
Title
Protection Area, Applicant Name
Patent Number
Date of Grant
pdf
431859
2019-11-20
BUP 11/2021
2021-05-31
Jarząbek D. M., Milczarek M., Dziekoński C.
Sposób wytwarzania sond pomiarowych do mikroskopów sił atomowych
PL, Instytut Podstawowych Problemów Techniki PAN
-
-
-
422789
2017-09-08
BUP 06/2019
2019-03-11
Kujawska T., Dera W., Dziekoński C.
Bimodalne urządzenie ultradźwiękowe do nieinwazyjnego niszczenia litych guzów nowotworowych u małych zwierząt
PL, Instytut Podstawowych Problemów Techniki PAN
233294
WUP 09/2019
2019-09-30



419571
2016-11-23
BUP 12/2018
2018-06-04
Jarząbek D.M., Dera W., Dziekoński C.
Urządzenie do pomiaru lepkości cienkich warstw materiałów lepkosprężystych
PL, Instytut Podstawowych Problemów Techniki PAN
230958
WUP 01/2019
2019-01-31