Partner: Qi Su


Ostatnie publikacje
1.Jingtao D., Rybak D., Su Q., Qiusheng W., Qifan Y., Jinlong G., Yuhang W., Nakielski P., Xianfeng W., Pierini F., Jianyong Y., Xiaoran L., Bin D., Sprayable Photothermal Fiber-Embedded Hydrogels to Engineer Microenvironment for Infected Wound Healing, Advanced Functional Materials, ISSN: 1616-301X, DOI: 10.1002/adfm.202501242, pp.2501242-1-14, 2025

Streszczenie:

The treatment of infected irregular wounds remains one of the most significant challenges in clinical practice. Sprayable hydrogels have attracted considerable attention due to their favorable fitting with irregular wounds. However, the development of hydrogels with programmable anti-bacterial, anti-inflammatory, and regenerative properties to match the healing process still faces severe challenges. Herein, a versatile strategy is demonstrated to develop sprayable and photothermal fiber-embedded hydrogel dressings by incorporating the gold nanorods (AuNRs) and anti-inflammatory drug diclofenac sodium (DS)-loaded poly(lactic-co-glycolic acid) (PLGA) electrospun fibers into the stromal-cell-derived factor 1α (SDF-1α)-immobilized gelatin methacrylate hydrogel. Benefiting from the photothermal conversion property of AuNRs and the suitable glass transition temperature of PLGA short fibers, the hydrogels can not only realize a photothermal anti-bacterial effect, but also photo-triggered on-demand release of DS for anti-inflammatory activity. Furthermore, the sustained release of SDF-1α facilitates endogenous stem cell recruitment. The in vivo experiments demonstrate accelerated healing of infected wounds. The RNA-sequencing analysis reveals that the hydrogel is capable of suppressing the inflammatory response-related pathway. The photo-responsive fiber-embedded hydrogels offer a promising strategy for constructing a photo-triggered programmable therapeutic platform for regenerative medicine.

Afiliacje autorów:

Jingtao D.-other affiliation
Rybak D.-IPPT PAN
Su Q.-other affiliation
Qiusheng W.-other affiliation
Qifan Y.-other affiliation
Jinlong G.-other affiliation
Yuhang W.-other affiliation
Nakielski P.-other affiliation
Xianfeng W.-other affiliation
Pierini F.-other affiliation
Jianyong Y.-other affiliation
Xiaoran L.-other affiliation
Bin D.-other affiliation
2.Zargarian S., Zakrzewska A., Kosik-Kozioł A., Bartolewska M., Shah S., Li X., Su Q., Petronella F., Marinelli M., De Sio L., Lanzi M., Ding B., Pierini F., Advancing resource sustainability with green photothermal materials: Insights from organic waste-derived and bioderived sources, nanotechnology reviews, ISSN: 2191-9097, DOI: 10.1515/ntrev-2024-0100, Vol.13, No.1, pp.20240100-1-39, 2024

Streszczenie:

Recently, there has been a surge of interest in developing new types of photothermal materials driven by the ongoing demand for efficient energy conversion, environmental concerns, and the need for sustainable solutions. However, many existing photothermal materials face limitations such as high production costs or narrow absorption bands, hindering their widespread application. In response to these challenges, researchers have redirected their focus toward harnessing the untapped potential of organic waste-derived and bioderived materials. These materials, with photothermal properties derived from their intrinsic composition or transformative processes, offer a sustainable and cost-effective alternative. This review provides an extended categorization of organic waste-derived and bioderived materials based on their origin. Additionally, we investigate the mechanisms underlying the photothermal properties of these materials. Key findings highlight their high photothermal efficiency and versatility in applications such as water and energy harvesting, desalination, biomedical applications, deicing, waste treatment, and environmental remediation. Through their versatile utilization, they demonstrate immense potential in fostering sustainability and support the transition toward a greener and more resilient future. The authors’ perspective on the challenges and potentials of platforms based on these materials is also included, highlighting their immense potential for real-world implementation.

Słowa kluczowe:

photothermal materials, organic waste valorization, bioderived materials

Afiliacje autorów:

Zargarian S.-IPPT PAN
Zakrzewska A.-IPPT PAN
Kosik-Kozioł A.-IPPT PAN
Bartolewska M.-IPPT PAN
Shah S.-IPPT PAN
Li X.-Donghua University (CN)
Su Q.-other affiliation
Petronella F.-other affiliation
Marinelli M.-other affiliation
De Sio L.-other affiliation
Lanzi M.-University of Bologna (IT)
Ding B.-Donghua University (CN)
Pierini F.-IPPT PAN
70p.