Partner: Jolanta Małyszko |
Ostatnie publikacje
1. | Golenia A.♦, Żołek N., Olejnik P.♦, Żebrowski P.♦, Małyszko J.♦, Patterns of Cognitive Impairment in Hemodialysis Patients and Related Factors including Depression and Anxiety, Journal of Clinical Medicine, ISSN: 2077-0383, DOI: 10.3390/jcm12093119, Vol.12, No.9, pp.3119-3119, 2023 Streszczenie: Introduction: Hemodialysis patients are at higher risk of developing cognitive impairment, but the pattern of affected cognitive domains is still undetermined. Little is also known about the symptoms of depression and anxiety in hemodialysis patients. Methods: In this cross-sectional study, we included 74 consecutive adult patients undergoing hemodialysis. Cognitive functions were assessed using the Addenbrooke Cognitive Test III. In addition, all patients were screened for symptoms of depression and anxiety using the Hospital Anxiety and Depression Scale. Results: The mean age of hemodialysis patients was 65.69 ± 14 years. Among the patients, there were 27% and 31% of patients with mild cognitive impairment and suspected dementia, respectively. In the group of patients with suspected dementia, all cognitive functions had significantly lower values compared to these functions in incognitively unimpaired and mild cognitive impairment patients. The most impaired domain was verbal fluency, which reflects impairments in executive function. Depression and anxiety symptoms were observed in 28% and 22% of patients, respectively. Patients with anxiety symptoms had higher levels of endogenous creatinine, parathyroid hormone, and hemoglobin, as well as decreased creatinine clearance, being younger and less educated. No factors contributing to the occurrence of depressive symptoms were found. Conclusion: Cognitive dysfunction is a significant problem in hemodialysis patients. Our study showed that the prevalence of cognitive impairment and depression and anxiety symptoms in hemodialysis patients was high. The domain of executive functions was most affected. Furthermore, creatinine, parathyroid hormone, hemoglobin levels, creatinine clearance, and education affected the anxiety scale score. Słowa kluczowe: hemodialysis,cognitive impairment,depression,anxiety Afiliacje autorów:
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2. | Golenia A.♦, Olejnik P.♦, Żołek N., Wojtaszek E.♦, Małyszko J.♦, Cognitive impairment and anxiety are prevalent in kidney transplant recipients : Cognitive function and anxiety after kidney transplantation, Kidney Blood Press Res , ISSN: 1420-4096, DOI: 10.1159/000533755, pp. - , 2023 Streszczenie: Introduction. Cognitive impairment (CI) is common in end-stage kidney disease (ESKD), including kidney transplant recipients. Patients with cognitive problems may find it difficult to comply with medical recommendations after kidney transplantation (KT), which can be the cause of many complications, poorer prognosis, and increased Słowa kluczowe: cognitive impairment,kidney transplantation,immunosuppressive therapy,ACE III test,HADS Afiliacje autorów:
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3. | Golenia A.♦, Żołek N.S., Olejnik P.♦, Wojtaszek E.♦, Głogowski T.♦, Małyszko J.♦, Prevalence of Cognitive Impairment in Peritoneal Dialysis Patients and Associated Factors, Kidney Blood Press Res , ISSN: 1420-4096, DOI: 10.1159/000530168, Vol.48, No.1, pp.202-208, 2023 Streszczenie: Background: Cognitive impairment (CI) in patients with chronic kidney disease, including those treated with renal replacement therapy, is a growing problem worldwide. Objectives: The study aimed to assess the prevalence of CI and associated factors in patients undergoing peritoneal dialysis (PD). Methods: In this cross-sectional study, 18 consecutive patients with PD therapy and 15 controls were evaluated for CI using the Addenbrooke’s Cognitive Examination III (ACE III) test. Results: The prevalence of CI was 33% in patients and 27% in the control group and was not statistically significant. A higher prevalence of CI was found in subjects aged ≥65 years old than in those <65 years old (p = 0.02), but only in the control group. The prevalence of CI in PD patients over and under 65 years of age did not differ statistically significantly (p = 0.12). Memory and verbal fluency were the most affected cognitive domain in PD patients with CI (p = 0.00, p = 0.04, respectively). There was a significant correlation between higher educated PD patients and the ACE III test results. The duration of dialysis did not affect the results of the cognitive screening test. Conclusions: CI is a growing problem in the course of chronic kidney disease and dialysis therapy. It seems that cognitive problems may occur in patients undergoing PD at a younger age than in the general population with particularly affected memory and verbal fluency. Higher educated patients score better on the cognitive screening test. Słowa kluczowe: Cognitive impairment,Chronic kidney disease,Peritoneal dialysis,Addenbrooke’s Cognitive Examination III test,Screening test Afiliacje autorów:
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