Partner: M. Versluis |
Recent publications
1. | Postema M.♦, Bouakaz A.♦, Versluis M.♦, de Jong N.♦, Ultrasound-Induced Gas Release from Contrast Agent Microbubbles, IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL, ISSN: 0885-3010, DOI: 10.1109/TUFFC.2005.1504026, Vol.52, No.6, pp.1035-1041, 2005 Abstract: We investigated gas release from two hard- shelled ultrasound contrast agents by subjecting them to high-mechanical index (MI) ultrasound and simultaneously capturing high-speed photographs. At an insonifying frequency of 1.7 MHz, a larger percentage of contrast bubbles is seen to crack than at 0.5 MHz. Most of the released gas bubbles have equilibrium diameters between 1.25 and 1.75 m. Their disappearance was observed optically. Free gas bubbles have equilibrium diameters smaller than the bubbles from which they have been released. Coalescence may account for the long dissolution times acoustically observed and published in previous studies. After sonic cracking, the cracked bubbles stay acoustically active. Keywords:Sonic cracking Affiliations:
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Conference papers
1. | Postema M.♦, Marmottant P.♦, Lancée C.T.♦, Versluis M.♦, Hilgenfeldt S.♦, de Jong N.♦, Ultrasound-induced coalescence of free gas microbubbles, IUS 2004, IEEE International Ultrasonics Symposium, 2004-08-23/08-27, Montreal (CA), DOI: 10.1109/ULTSYM.2004.1417653, Vol.1, pp.1-4, 2004 Abstract: When gas bubbles collide, the following stages of bubble coalescence have been reported: flattening of the opposing bubble surfaces prior to contact, drainage of the interposed liquid film toward a critical minimal thickness, rupture of the liquid film, and formation of a single bubble. During insonification, expanding contrast agent microbubbles may collide with each other, resulting in coalescence or bounce.
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2. | de Jong N.♦, Bouakaz A.♦, van Wamel A.♦, Postema M.♦, Versluis M.♦, Microbubbles for ultrasound imaging and therapy, Workshop on Ultrasound in Biomeasurements, Diagnostics and Therapy, Vol.2, pp.123-126, 2004 |