| Partner: M.P. Mienkina |
Recent publications
| 1. | Mienkina M.P.♦, Postema M.♦, Hansen C.♦, Schmitz G.♦, Modelling ultrasonic backscattering of an SPIO-MRI contrast agent, Biomedical Engineering-Biomedizinische Technik, ISSN: 1862-278X, Vol.50, No.S1, Supplement, pp.750-751, 2005 Abstract: The ultrasonic backscatter coefficient (BSC) of superparamagnetic iron oxide (SPIO) nanoparticles, which are used as a liver MRI contrast agent, was simulated using a Yagi backscattering model. The BSC of SPIO cores that are aggregated in the lysosomes of Kupffer cells is significantly higher (85 dB) than the BSC of non- aggregated SPIO cores. Considering in vivo concentrations, the aggregated SPIO does not elevate the BSC of the liver markedly (9x10-6 dB). Thus, the reported visibility of SPIO in clinical ultrasound cannot be explained by classical scattering theory. Other non-linear effects need to be taken into account. Affiliations:
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List of chapters in recent monographs
| 1. 463 | Hiltawsky K.M.♦, Haisch C.♦, Mienkina M.P.♦, Postema M.♦, Schmitz G.♦, Health Academy, Molecular imaging: Innovationen und Visionen in der medizinischen Bildgebung, rozdział: Optoakustik in der medizinischen Bildgebung, pp.159-175, 2006 |